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Tapio, S.

Pathology and biology of radiation-induced cardiac disease.

J. Radiat. Res. 57, 439-448 (2016)
Verlagsversion DOI PMC
Open Access Gold
Creative Commons Lizenzvertrag
Heart disease is the leading global cause of death. The risk for this disease is significantly increased in populations exposed to ionizing radiation, but the mechanisms are not fully elucidated yet. This review aims to gather and discuss the latest data about pathological and biological consequences in the radiation-exposed heart in a comprehensive manner. A better understanding of the molecular and cellular mechanisms underlying radiation-induced damage in heart tissue and cardiac vasculature will provide novel targets for therapeutic interventions. These may be valuable for individuals clinically or occupationally exposed to varying doses of ionizing radiation.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Korrespondenzautor
Schlagwörter Cardiac Disease ; Endothelial Cell ; Heart ; Ionizing Radiation ; Myocardium; Induced Heart-disease; Inflammatory Plaque Phenotype; Human Endothelial-cells; Von-willebrand-factor; Ionizing-radiation; Cardiovascular-disease; Apoe(-/-) Mice; Breast-cancer; Rat-heart; In-vitro
ISSN (print) / ISBN 0449-3060
e-ISSN 1349-9157
Zeitschrift Journal of Radiation Research
Quellenangaben Band: 57, Heft: 5, Seiten: 439-448 Artikelnummer: , Supplement: ,
Verlag Oxford University Press
Verlagsort Oxford
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Radiation Biology (ISB)