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Adler, B.* ; Sattler, C. ; Adler, H.

Herpesviruses and their host cells: A successful liaison.

Trends Microbiol., DOI: 10.1016/j.tim.2016.11.009 (2016)
Postprint DOI
Open Access Green
During a long history of coevolution, herpesviruses have reached a fine-tuned balance with their hosts, allowing them to successfully persist and spread to new hosts without causing too much damage. Only under certain circumstances, as in neonates or immunocompromised individuals, they may cause serious diseases. The delicate balance between herpesviruses and their hosts results from interactions of a great variety of viral and cellular factors which together shape the tropism for a particular host, tissue, or cell. Understanding these interactions will provide insight into the viral life cycle and cell biology in general. Moreover, it will also facilitate comprehension of herpesvirus pathogenesis, enabling the development of new strategies to combat herpesviruses in cases where they cause disease.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter herpesviruses, tropism, cell and tissue types, restriction factors
ISSN (print) / ISBN 0966-842X
e-ISSN 1878-4380
Zeitschrift Trends in microbiology
Verlag Cell Press
Verlagsort Cambridge, Mass.
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Research Unit Lung Repair and Regeneration (LRR)