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Recent advances in treating Parkinson's disease.

F1000 Res. 6:260 (2017)
Verlagsversion DOI PMC
Open Access Gold
Creative Commons Lizenzvertrag
This article summarizes (1) the recent achievements to further improve symptomatic therapy of motor Parkinson's disease (PD) symptoms, (2) the still-few attempts to systematically search for symptomatic therapy of non-motor symptoms in PD, and (3) the advances in the development and clinical testing of compounds which promise to offer disease modification in already-manifest PD. However, prevention (that is, slowing or stopping PD in a prodromal stage) is still a dream and one reason for this is that we have no consensus on primary endpoints for clinical trials which reflect the progression in prodromal stages of PD, such as in rapid eye movement sleep behavior disorder (RBD) -a methodological challenge to be met in the future.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Schlagwörter Parkinson's Disease ; Disease Modifying Treatment ; Motor Symptoms ; Non-motor Symptoms ; Prodromal Stage
Sprache englisch
Veröffentlichungsjahr 2017
HGF-Berichtsjahr 2017
e-ISSN 2046-1402
Quellenangaben Band: 6, Heft: , Seiten: , Artikelnummer: 260 Supplement: ,
Verlagsort London
Begutachtungsstatus Peer reviewed
POF Topic(s) 30205 - Bioengineering and Digital Health
Forschungsfeld(er) Genetics and Epidemiology
PSP-Element(e) G-503200-001
PubMed ID 28357055
Scopus ID 85017120192
Erfassungsdatum 2017-06-19