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Mascher, M.* ; Gundlach, H. ; Himmelbach, A.* ; Beier, S.* ; Twardziok, S.O. ; Wicker, T.* ; Radchuk, V.* ; Dockter, C.* ; Hedley, P.E.* ; Russell, J.A.* ; Bayer, M.* ; Ramsay, L.* ; Liu, H.* ; Haberer, G. ; Zhang, X.Q.* ; Zhang, Q.* ; Barrero, R.A.* ; Li, L.* ; Taudien, S.* ; Groth, M.* ; Felder, M.* ; Hastie, A.* ; Šimková, H.* ; Staňková, H.* ; Vrána, J.* ; Chan, S.W.* ; Muñoz-Amatriaín, M.* ; Ounit, R.* ; Wanamaker, S.* ; Bolser, D.* ; Colmsee, C.* ; Schmutzer, T.* ; Aliyeva-Schnorr, L.* ; Grasso, S.* ; Tanskanen, J.* ; Chailyan, A.* ; Sampath, D.* ; Heavens, D.* ; Clissold, L.* ; Cao, S.* ; Chapman, B.* ; Dai, F.* ; Han, Y.* ; Li, H.* ; Li, X.* ; Lin, C.* ; McCooke, J.K.* ; Tan, C.S.* ; Wang, P.* ; Wang, S.* ; Yin, S.* ; Zhou, G.* ; Poland, J.A.* ; Bellgard, M.I.* ; Borisjuk, L.* ; Houben, A.* ; Doležel, J.* ; Ayling, S.* ; Lonardi, S.* ; Kersey, P.* ; Langridge, P.* ; Muehlbauer, G.J.* ; Clark, M.D.* ; Caccamo, M.* ; Schulman, A.H.* ; Mayer, K.F.X.* ; Platzer, M.* ; Close, T.J.* ; Scholz, U.* ; Hansson, M.* ; Zhang, G.* ; Braumann, I.* ; Spannagl, M. ; Li, C.* ; Waugh, R.* ; Stein, N.*

A chromosome conformation capture ordered sequence of the barley genome.

Nature 544, 427-433 (2017)
Verlagsversion Forschungsdaten DOI PMC
Open Access Gold (Paid Option)
Creative Commons Lizenzvertrag
Cereal grasses of the Triticeae tribe have been the major food source in temperate regions since the dawn of agriculture. Their large genomes are characterized by a high content of repetitive elements and large pericentromeric regions that are virtually devoid of meiotic recombination. Here we present a high-quality reference genome assembly for barley (Hordeum vulgare L.). We use chromosome conformation capture mapping to derive the linear order of sequences across the pericentromeric space and to investigate the spatial organization of chromatin in the nucleus at megabase resolution. The composition of genes and repetitive elements differs between distal and proximal regions. Gene family analyses reveal lineage-specific duplications of genes involved in the transport of nutrients to developing seeds and the mobilization of carbohydrates in grains. We demonstrate the importance of the barley reference sequence for breeding by inspecting the genomic partitioning of sequence variation in modern elite germplasm, highlighting regions vulnerable to genetic erosion.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter Bacterial Artificial Chromosomes; Inverted-repeat Elements; Complex-plant Genomes; Hi-c; Environmental Adaptation; Ltr Retrotransposons; Structural Variation; Maize Genome; Software; Database
ISSN (print) / ISBN 0028-0836
e-ISSN 1476-4687
Zeitschrift Nature
Quellenangaben Band: 544, Heft: 7651, Seiten: 427-433 Artikelnummer: , Supplement: ,
Verlag Nature Publishing Group
Verlagsort London
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed