PuSH - Publikationsserver des Helmholtz Zentrums München

Moor, V.* ; Wagner, R. ; Sayer, M.* ; Petsch, M.* ; Rueb, S. ; Häring, H.-U. ; Heyne, N. ; Artunc, F.

Routine monitoring of sodium and phosphorus removal in peritoneal dialysis (PD) patients treated with continuous ambulatory PD (CAPD), automated PD (APD) or combined CAPD plus APD.

Kidney Blood Press. Res. 42, 257-266 (2017)
Verlagsversion DOI PMC
Open Access Gold
Creative Commons Lizenzvertrag
Background: Adequate removal of sodium (Na) and phosphorus (P) is of paramount importance for patients with dialysis-dependent kidney disease can easily quantified in peritoneal dialysis (PD) patients. Some studies suggest that automated PD (APD) results in lower Na and P removal. Methods. In this study we retrospectively analysed our data on Na and P removal in PD patients after implementation of a routine monitoring in 2011. Patients were stratified in those treated with continuous ambulatory PD (CAPD, n=24), automated PD (APD, n=23) and APD with one bag change (CAPD+APD, n=10). Until 2015 we collected time-varying data on Na and P removal from each patient (median 5 [interquartile range 4-8] values). Results: Peritoneal Na and P removal (mmol per 24h +/- standard deviation) was 102 +/- 48 and 8 +/- 2 in the CAPD, 90 +/- 46 and 9 +/- 3 in the APD and 126 +/- 39 and 13 +/- 2 in the CAPD+APD group (ANOVA P=0.141 and <0.001). Taking renal excretion into account total Na and P removal (mmol per 24h) was 221 +/- 65 and 16 +/- 5 in the CARD, 189 +/- 58 and 17 +/- 6 in the APD and 183 +/- 38 and 16 +/- 6 in the CAPD+APD group (P=0.107 and 0.764). Over time, peritoneal removal of Na but not that of P increased in all groups. In patients with modifications of PD treatment, Na but not P removal was significantly increased over-time. Conclusions: Overall Na and P removal were similar with different PD modalities. Individualized adjustments of PD prescription including icodextrin use or higher glucose concentration can improve Na removal while P removal is mainly determined by the dialysate volume.
Altmetric
Weitere Metriken?
[➜Einloggen]
Zusatzinfos bearbeiten [➜Einloggen]
Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter Apd ; Capd Plus Apd ; Capd ; Phosphorus ; Peritoneal Dialysis ; Sodium; Hemodialysis; Phosphate; Ultrafiltration; Metabolism; Mortality; Outcomes
ISSN (print) / ISBN 1420-4096
e-ISSN 1423-0143
Zeitschrift Kidney & Blood Pressure Research
Quellenangaben Band: 42, Heft: 2, Seiten: 257-266 Artikelnummer: , Supplement: ,
Verlag Karger
Verlagsort Basel
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Diabetes Research and Metabolic Diseases (IDM)