The macromolecular mechanics of GLP-1 with its cell surface receptor came into focus as two landmark publications recently published in Nature collectively herald advancement in structure-based design for a receptor class of great therapeutic importance (Jazayeri et al., 2017; Zhang et al., 2017).
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SchlagwörterCryoelectron Microscopy ; Glp-1 ; Gpcr Family B ; Incretin ; Structure-based Drug Design