PuSH - Publikationsserver des Helmholtz Zentrums München

Export: TXT Text RIS Endnote (RIS) BIB BibTeX
Tokarz, J. ; Haid, M. ; Cecil, A. ; Prehn, C. ; Artati, A. ; Möller, G. ; Adamski, J.

Endocrinology meets metabolomics: Achievements, pitfalls, and challenges.

Trends Endocrinol. Metab. 28, 705-721 (2017)
Postprint DOI PMC
Open Access Green
The metabolome, although very dynamic, is sufficiently stable to provide specific quantitative traits related to health and disease. Metabolomics requires balanced use of state-of-the-art study design, chemical analytics, biostatistics, and bioinformatics to deliver meaningful answers to contemporary questions in human disease research. The technology is now frequently employed for biomarker discovery and for elucidating the mechanisms underlying endocrine-related diseases. Metabolomics has also enriched genome-wide association studies (GWAS) in this area by providing functional data. The contributions of rare genetic variants to metabolome variance and to the human phenotype have been underestimated until now.
Impact Factor
Scopus SNIP
Web of Science
Times Cited
Scopus
Cited By
Altmetric
10.893
2.264
19
24
Tags
Anmerkungen
Besondere Publikation
Auf Hompepage verbergern

Zusatzinfos bearbeiten
Eigene Tags bearbeiten
Privat
Eigene Anmerkung bearbeiten
Privat
Auf Publikationslisten für
Homepage nicht anzeigen
Als besondere Publikation
markieren
Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Gwas ; Biostatistics ; Endocrinology ; Genomics ; Mass Spectrometry ; Metabolomics; Reveals Potential Biomarkers; Polyunsaturated Fatty-acids; Type-2 Diabetes-mellitus; Genome-wide Association; Human Blood Metabolites; Negative Breast-cancer; Ovarian Endometriosis; Childhood Obesity; Multivariate-analysis; Missing Heritability
Sprache
Veröffentlichungsjahr 2017
HGF-Berichtsjahr 2017
ISSN (print) / ISBN 1043-2760
e-ISSN 1879-3061
Zeitschrift Trends in Endocrinology and Metabolism
Quellenangaben Band: 28, Heft: 10, Seiten: 705-721 Artikelnummer: , Supplement: ,
Verlag Elsevier
Verlagsort London
Begutachtungsstatus Peer reviewed
Institut(e) Molekulare Endokrinologie und Metabolismus (MEM)
POF Topic(s) 30201 - Metabolic Health
Forschungsfeld(er) Genetics and Epidemiology
PSP-Element(e) G-505600-003
DOI 10.1016/j.tem.2017.07.001
WOS ID WOS:000411131100002
Scopus ID 85026679812
PubMed ID 28780001
Erfassungsdatum 2017-09-13
[➜Korrektur melden]