möglich sobald bei der ZB eingereicht worden ist.
RAS oncogenes direct metastasis.
Mol. Cell. Oncol. 4:e1345711 (2017)
RAS genes are cardinal driver oncogenes frequently and differentially mutated across bodily tumors. Their tumorigenic potential has been mainly ascribed to autonomous promotion of tumor cell proliferation and survival. However, recent evidence shows that RAS oncogenes also function to define metastatic tropism. Interestingly, RAS-driven metastasis is mediated by distinct chemokine sets that signal to endothelial and myeloid cells.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Schlagwörter
Chemokines ; Kras ; Lung Metastasis ; Malignant Pleural Effusion ; Nras
e-ISSN
2372-3556
Zeitschrift
Molecular & Cellular Oncology
Quellenangaben
Band: 4,
Heft: 5,
Artikelnummer: e1345711
Verlag
Taylor & Francis
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed
Institut(e)
Lung Health and Immunity (LHI)