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Huang, C.* ; Moran, A.E.* ; Coxson, P.G.* ; Yang, X.* ; Liu, F.* ; Cao, J.* ; Chen, K. ; Wang, M.* ; He, J.* ; Goldman, L.* ; Zhao, D.* ; Kinney, P.L.* ; Gu, D.*

Potential cardiovascular and total mortality benefits of air pollution control in Urban China.

Circulation 136, 1575-1584 (2017)
Verlagsversion Postprint Forschungsdaten DOI PMC
Open Access Green
Background -Outdoor air pollution ranks fourth among preventable causes of China's burden of disease. We hypothesized that the magnitude of health gains from air quality improvement in urban China could compare with achieving recommended blood pressure or smoking control goals. Methods -The Cardiovascular Disease Policy Model-China projected coronary heart disease, stroke, and all-cause deaths in urban Chinese adults aged 35-84 years from 2017 to 2030 if recent air quality (particulate matter with aerodynamic diameter ≤ 2.5 μm, PM2.5) and traditional cardiovascular risk factor trends continue. We projected life years gained if urban China were to reach one of three air quality goals: Beijing Olympic Games level (mean PM2.5, 55 μg/m(3)), China Class II standard (35 μg/m(3)), or World Health Organization (WHO) standard (10 μg/m(3)). We compared projected air pollution reduction control benefits with potential benefits of reaching WHO hypertension and tobacco control goals. Results -Mean PM2.5 reduction to Beijing Olympic levels by 2030 would gain about 241,000 (95% uncertainty interval, 189,000-293,000) life-years annually. Achieving either the China Class II standard or WHO PM2.5 standard would yield greater health benefits [992,000 (95% uncertainty interval, 790,000-1,180,000) or 1,827,000 (95% uncertainty interval, 1,481,000-2,129,000) annual life years gained, respectively] than WHO-recommended goals of 25% improvement in systolic hypertension control and 30% reduction in smoking combined [928,000 (95% uncertainty interval, 830,000-1,033,000) life years]. Conclusions -Air quality improvement at different scenarios could lead to graded health benefits ranging from 241,000 life-years gained to much greater benefits are equal to or greater than the combined benefits of 25% improvement in systolic hypertension control and 30% smoking reduction.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter China ; Air Pollution ; Cardiovascular Disease ; Computer Modeling ; Health Benefits; Long-term Exposure; Fine Particulate Matter; Coronary-heart-disease; Extended Follow-up; Harvard 6 Cities; Global Burden; California Teachers; Public-health; Cohort; Risk
ISSN (print) / ISBN 0009-7322
e-ISSN 1524-4539
Zeitschrift Circulation
Quellenangaben Band: 136, Heft: 17, Seiten: 1575-1584 Artikelnummer: , Supplement: ,
Verlag Lippincott Williams & Wilkins
Verlagsort Philadelphia
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Epidemiology II (EPI2)