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Symvoulidis, P. ; Lauri, A. ; Stefanoiu, A.* ; Cappetta, M. ; Schneider, S.* ; Jia, H.* ; Stelzl, A. ; Koch, M. ; Perez, C.C. ; Myklatun, A. ; Renninger, S.* ; Chmyrov, A. ; Lasser, T.* ; Wurst, W. ; Ntziachristos, V. ; Westmeyer, G.G.

NeuBtracker-imaging neurobehavioral dynamics in freely behaving fish.

Nat. Methods 14, 1079-1082 (2017)
DOI PMC
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
A long-standing objective in neuroscience has been to image distributed neuronal activity in freely behaving animals. Here we introduce NeuBtracker, a tracking microscope for simultaneous imaging of neuronal activity and behavior of freely swimming fluorescent reporter fish. We showcase the value of NeuBtracker for screening neurostimulants with respect to their combined neuronal and behavioral effects and for determining spontaneous and stimulus-induced spatiotemporal patterns of neuronal activation during naturalistic behavior.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Light-sheet Microscopy; Brain Activity; Embryonic-development; Neuronal-activity; Larval Zebrafish; Neural Activity; Perception; Receptor
ISSN (print) / ISBN 1548-7091
e-ISSN 1548-7105
Zeitschrift Nature Methods
Quellenangaben Band: 14, Heft: 11, Seiten: 1079-1082 Artikelnummer: , Supplement: ,
Verlag Nature Publishing Group
Verlagsort New York, NY
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Biological and Medical Imaging (IBMI)
Institute of Developmental Genetics (IDG)