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Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Glial control of neurogenesis.
Curr. Opin. Neurobiol. 47, 188-195 (2017)
Glial cells are central components of all neurogenic niches in the embryonic as well as in the adult central nervous system. While neural stem cells (NSCs) themselves exhibit glial features the behavior of NSCs is also strongly influenced by niche glial cells. Recently, studies have begun to uncover a large variety of glial cell-extrinsic as well as intrinsic factors that play crucial roles in the control of NSCs and the regulation of the cellular output from the neurogenic niches. In this review, we focus on mechanisms underlying the formation of adult NSCs by embryonic radial glia cells, discuss the influence of niche glia cells on adult NSCs and examine how the neurogenic potential of glial cells is controlled.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Review
Schlagwörter
Neural Stem-cells; Adult Hippocampal Neurogenesis; In-vitro; Subventricular Zone; Subependymal Zone; Embryonic Origin; Reactive Gliosis; Ependymal Cells; Olfactory-bulb; Injured Brain
ISSN (print) / ISBN
0959-4388
e-ISSN
1873-6882
Zeitschrift
Current Opinion in Neurobiology
Quellenangaben
Band: 47,
Seiten: 188-195
Verlag
Elsevier
Verlagsort
London
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Stem Cell Research (ISF)