The aim of the International Commission on Radiological Protection (ICRP) is to protect humans against cancer and other diseases and effects associated with exposure to ionising radiation, and also to protect the environment, without unduly limiting the beneficial use of ionising radiation. As of the second half of 2017, four committees are contributing to the overall mission of ICRP, including Committee 1 (Radiation Effects). The role of Committee 1 includes consideration of the risks and mechanisms of induction of cancer and heritable disease; discussion of the risks, severity, and mechanisms of induction of tissue/organ damage and developmental defects; and review of the effects of ionising radiation on non-human biota at population level. This paper gives an overview of the recent activities of Committee 1, and discusses the focus of its active task groups.