möglich sobald bei der ZB eingereicht worden ist.
Modeling the volume change in mitochondria.
Int. J. Biomath. Biostat. 1, 53-62 (2010)
Mitochondrial swelling due to permeability transition is an important biological phenomenon with a lot of open questions. We give a new mathematical approach to model the volume change during the process. As opposed to the existing models we do not use differential equations, just basic assumptions about the swelling of a single mitochondrion and its cumulative effect. The results accurately describe the experimental swelling curves and are in accordance with previous findings. They also provide more insight into the nature of the positive feedback in the process. Due to its simplicity the method can be used for other biochemical or population dynamical processes as well.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Schlagwörter
Mitochondrial swelling; Mathematical modeling; Parameter estimation; Feedback
ISSN (print) / ISBN
0973-7340
Quellenangaben
Band: 1,
Heft: 1,
Seiten: 53-62
Verlag
Serials Publ.
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed