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Koch, M. ; Symvoulidis, P. ; Ntziachristos, V.

Tackling standardization in fluorescence molecular imaging.

Nat. Photonics 12, 505-515 (2018)
DOI
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
The emerging clinical use of targeted fluorescent agents heralds a shift in intraoperative imaging practices that overcome the limitations of human vision. However, in contrast to established radiological methods, no appropriate performance specifications and standards have been established in fluorescence molecular imaging. Moreover, the dependence of fluorescence signals on many experimental parameters and the use of wavelengths ranging from the visible to short-wave infrared (400–1,700 nm) complicate quality control in fluorescence molecular imaging. Here, we discuss the experimental parameters that critically affect fluorescence molecular imaging accuracy, and introduce the concept of high-fidelity fluorescence imaging as a means for ensuring reliable reproduction of fluorescence biodistribution in tissue.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Schlagwörter In-vivo; Quantum Dots; Optical-properties; Modulated Iccd; Real-time; Cancer; Performance; Disease; Tumors; Brain
Sprache englisch
Veröffentlichungsjahr 2018
HGF-Berichtsjahr 2018
ISSN (print) / ISBN 1749-4885
e-ISSN 1749-4893
Zeitschrift Nature Photonics
Quellenangaben Band: 12, Heft: 9, Seiten: 505-515 Artikelnummer: , Supplement: ,
Verlag Nature Publishing Group
Verlagsort Macmillan Building, 4 Crinan St, London N1 9xw, England
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Biological and Medical Imaging (IBMI)
POF Topic(s) 30205 - Bioengineering and Digital Health
Forschungsfeld(er) Enabling and Novel Technologies
PSP-Element(e) G-505500-001
DOI 10.1038/s41566-018-0221-5
WOS ID WOS:000443022200009
Scopus ID 85052728015
Erfassungsdatum 2018-09-10
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