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Huang, Y. ; Kellnberger, S. ; Sergiadis, G. ; Ntziachristos, V.

Blood vessel imaging using radiofrequency-induced second harmonic acoustic response.

Sci. Rep. 8:15522 (2018)
Verlagsversion DOI
Open Access Gold
Creative Commons Lizenzvertrag
We introduce a contrast mechanism for visualizing blood vessels based on radiofrequency-induced second harmonic acoustic (RISHA) signals sensing blood conductivity. We develop a novel imaging system using commonly available inexpensive components, and demonstrate in vivo RISHA visualization of blood vessels based on low-power quasi-continuous radiofrequency excitation of tissue at frequencies of a few MHz. We show how the novel approach also implicitly enables radiofrequency-induced passive ultrasound imaging and can be readily applied to non-invasive imaging of blood vessels ex vivo and in vivo. We discuss the implications of non-invasive conductivity measurements in the context of biomedical applications.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter Thermoacoustic Tomography; Biological Tissues; Breast-cancer; Optoacoustic Mesoscopy; Dielectric-properties; Real-time; Contrast; Conductivity; Feasibility; Enhancement
ISSN (print) / ISBN 2045-2322
e-ISSN 2045-2322
Zeitschrift Scientific Reports
Quellenangaben Band: 8, Heft: 1, Seiten: , Artikelnummer: 15522 Supplement: ,
Verlag Nature Publishing Group
Verlagsort London
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Biological and Medical Imaging (IBMI)