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Mahmutovic, L.* ; Akcesme, B.* ; Durakovic, C.* ; Akcesme, F.B.* ; Maric, A.* ; Adilovic, M.* ; Hamad, N.* ; Wjst, M. ; Feeney, O.* ; Semiz, S.*

Perceptions of students in health and molecular life sciences regarding pharmacogenomics and personalized medicine.

Hum. Genomics 12:50 (2018)
Verlagsversion DOI PMC
Open Access Gold
Creative Commons Lizenzvertrag
BackgroundIncreasing evidence is demonstrating that a patient's unique genetic profile can be used to detect the disease's onset, prevent its progression, and optimize its treatment. This led to the increased global efforts to implement personalized medicine (PM) and pharmacogenomics (PG) in clinical practice. Here we investigated the perceptions of students from different universities in Bosnia and Herzegovina (BH) towards PG/PM as well as related ethical, legal, and social implications (ELSI). This descriptive, cross-sectional study is based on the survey of 559 students from the Faculties of Medicine, Pharmacy, Health Studies, Genetics, and Bioengineering and other study programs.ResultsOur results showed that 50% of students heard about personal genome testing companies and 69% consider having a genetic test done. A majority of students (57%) agreed that PM represents a promising healthcare model, and 40% of students agreed that their study program is well designed for understanding PG/PM. This latter opinion seems to be particularly influenced by the field of study (7.23, CI 1.99-26.2, p=0.003). Students with this opinion are also more willing to continue their postgraduate education in the PM (OR=4.68, CI 2.59-8.47, p<0.001). Furthermore, 45% of students are aware of different ethical aspects of genetic testing, with most of them (46%) being concerned about the patient's privacy.ConclusionsOur results indicate a positive attitude of biomedical students in Bosnia and Herzegovina towards genetic testing and personalized medicine. Importantly, our results emphasize the key importance of pharmacogenomic education for more efficient translation of precision medicine into clinical practice.
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Web of Science
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3.500
0.686
10
12
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Precision Medicine ; Pharmacogenomics ; Education ; Ethical ; Legal ; And Social Issues ; Survey; Ethical-issues; Care; Pharmacists; Education; Genetics; Future; Legal; Views; Us; Implementation
Sprache englisch
Veröffentlichungsjahr 2018
HGF-Berichtsjahr 2018
ISSN (print) / ISBN 1473-9542
e-ISSN 1479-7364
Zeitschrift Human genomics
Quellenangaben Band: 12, Heft: 1, Seiten: , Artikelnummer: 50 Supplement: ,
Verlag Stewart
Verlagsort London
Begutachtungsstatus Peer reviewed
POF Topic(s) 30202 - Environmental Health
Forschungsfeld(er) Lung Research
PSP-Element(e) G-505000-003
Scopus ID 85056552694
PubMed ID 30424805
Erfassungsdatum 2018-11-19