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Slachtova, H.* ; Gehring, U.* ; Hoek, G.* ; Tomaskova, H.* ; Luttmann-Gibson, H.* ; Moshammer, H.* ; Paldy, A.* ; Pattenden, S.* ; Slotova, K.* ; Speizer, F.* ; Zlotkowska, R.* ; Heinrich, J.

Parental education and lung function of children in the PATY study.

Eur. J. Epidemiol. 26, 45-54 (2011)
DOI PMC
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Studies of the relationships between low socio-economic status and impaired lung function were conducted mainly in Western European countries and North America. East-West differences remain unexplored. Associations between parental education and lung function were explored using data on 24,010 school-children from eight cross-sectional studies conducted in North America, Western and Eastern Europe. Parental education was defined as low and high using country-specific classifications. Country-specific estimates of effects of low parental education on volume and flow parameters were obtained using linear and logistic regression, controlling for early life and other individual risk factors. Meta-regressions were used for assessment of heterogeneity between country-specific estimates. The association between low parental education and lung function was not consistent across the countries, but showed a more pronounced inverse gradient in the Western countries. The most consistent decrease associated with low parental education was found for peak expiratory flow (PEF), ranging from -2.80 to -1.14%, with statistically significant associations in five out of eight countries. The mean odds ratio for low PEF (<75% of predicted) was 1.34 (95% CI 1.06-1.70) after all adjustments. Although social gradients were attenuated after adjusting for known risk factors, these risk factors could not completely explain the social gradient in lung function.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Lung function; Parental education; Combined analysis; East-West differences; PATY study; Children
Sprache englisch
Veröffentlichungsjahr 2011
HGF-Berichtsjahr 2011
ISSN (print) / ISBN 0393-2990
e-ISSN 1573-7284
Quellenangaben Band: 26, Heft: 1, Seiten: 45-54 Artikelnummer: , Supplement: ,
Verlag Springer
Verlagsort Dordrecht, Netherlands
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Epidemiology (EPI)
POF Topic(s) 30503 - Chronic Diseases of the Lung and Allergies
Forschungsfeld(er) Genetics and Epidemiology
PSP-Element(e) G-503900-001
PubMed ID 20882323
Scopus ID 79151476362
Erfassungsdatum 2011-05-19