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Eidemüller, M. ; Simonetto, C. ; Kundrat, P. ; Ulanowski, A. ; Shemiakina, E. ; Güthlin, D. ; Rennau, H.* ; Remmele, J.* ; Hildebrandt, G.* ; Wolf, U.*

Long-term health risk after breast-cancer radiotherapy: Overview of passos methodology and software.

Radiat. Prot. Dosim., DOI: 10.1093/rpd/ncy219 (2018)
Postprint DOI PMC
Open Access Green
Breast-cancer radiotherapy reduces the recurrence rates and improves patient survival. However, it also increases the incidence of second cancers and of heart disease. These radiation-induced long-term health risks become increasingly important with improved cure rates and prolonged patient survival. Radiation doses to nearby as well as distant organs strongly vary between different irradiation techniques and among individual patients. To provide personalized lifetime risk estimates, the German national project PASSOS combines individual anatomy, dosimetric estimates, organ-specific low- and high-dose risk models and personal risk factors such as smoking. A dedicated software tool is under development to assist clinical decision-making processes.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Sprache englisch
Veröffentlichungsjahr 2018
HGF-Berichtsjahr 2018
ISSN (print) / ISBN 0144-8420
e-ISSN 1742-3406
Zeitschrift Radiation Protection Dosimetry
Verlag Oxford University Press
Verlagsort Oxford
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Radiation Protection (ISS)
POF Topic(s) 30504 - Mechanisms of Genetic and Environmental Influences on Health and Disease
Forschungsfeld(er) Radiation Sciences
PSP-Element(e) G-501100-004
DOI 10.1093/rpd/ncy219
PubMed ID 30520982
Erfassungsdatum 2018-12-13
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