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Psycharakis, S.E.* ; Liapis, E. ; Zacharopoulos, A.* ; Oraiopoulou, M.E.* ; Papamatheakis, J.* ; Sakkalis, V.* ; Zacharakis, G.*

High resolution volumetric imaging of primary and secondary tumor spheroids using multi-angle Light Sheet Fluorescence Microscopy (LSFM).

Conf. Proc. IEEE Eng. Med. Biol. Soc. 2018, 866-869 (2018)
DOI
Breast cancer and Glioblastoma brain cancer are severe malignancies with poor prognosis. In this study, primary Glioblastoma and secondary breast cancer spheroids are formed and treated with the well-known Temozolomide and Doxorubicin chemotherapeutics, respectively. High resolution imaging of both primary and secondary cancer cell spheroids is possible using a custom multi-angle Light Sheet Fluorescence Microscope. Such a technique is successful in realizing preclinical drug screening, while enables the discrimination among physiologic tumor parameters.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
ISSN (print) / ISBN 1557-170X
Konferenztitel 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018
Konferzenzdatum 18-21 July 2018
Konferenzort Hawaii, Honolulu
Zeitschrift Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Quellenangaben Band: 2018, Heft: , Seiten: 866-869 Artikelnummer: , Supplement: ,
Verlag Institute of Electrical and Electronics Engineers (IEEE)
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Biological and Medical Imaging (IBMI)