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Artati, A. ; Prehn, C. ; Adamski, J.

LC-MS/MS-based metabolomics for cell cultures.

In: Cell-Based Assays Using iPSCs for Drug Development and Testing. Berlin [u.a.]: Springer, 2019. 119-130 (Methods Mol. Biol. ; 1994)
DOI PMC
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Metabolomics, a comprehensive analysis of metabolites in biological specimens (e.g., cells, body fluids, tissues, exhaled air, plants), offers promising tools in health, nutrition, biotechnology, and food sciences. Here we describe methods of LC-MS/MS-based analyses for cell metabolomics. Using methods employed in this section, over 1000 endogenous and exogenous metabolites can be detected, annotated, and quantified relatively by nontargeted analysis approach, whereas targeted metabolomics analysis enables us to quantify 188 endogenous metabolites.
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Publikationstyp Artikel: Sammelbandbeitrag/Buchkapitel
Schlagwörter Cell Culture Metabolomics ; Lc-ms/ms-based Metabolomics ; Mass Spectrometry ; Metabolomics ; Nontargeted Metabolomics ; Targeted Metabolomics
ISSN (print) / ISBN 1064-3745
e-ISSN 1940-6029
Bandtitel Cell-Based Assays Using iPSCs for Drug Development and Testing
Zeitschrift Methods in Molecular Biology
Quellenangaben Band: 1994, Heft: , Seiten: 119-130 Artikelnummer: , Supplement: ,
Verlag Springer
Verlagsort Berlin [u.a.]
Begutachtungsstatus Peer reviewed
Institut(e) Molekulare Endokrinologie und Metabolismus (MEM)