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Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Genome-wide association studies of atrial fibrillation: Past, present, and future.
Cardiovasc. Res. 89, 701-709 (2011)
Genome-wide association studies (GWAS) for atrial fibrillation (AF) have identified three distinct genetic loci on chromosomes 1q21, 4q25, and 16q22 that are associated with the arrhythmia. Susceptibility loci also have been identified by GWAS for PR interval duration, a quantitative phenotype related to AF. In this review article, we have sought to summarize the latest findings for population-based genetic studies of AF, to highlight ongoing functional studies, and to explore the future directions of genetic research on AF.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Schlagwörter
Atrial fibrillation; Genetics; Genome-wide association study; Single nucleotide polymorphism; Arrhythmia
ISSN (print) / ISBN
0008-6363
e-ISSN
1755-3245
Zeitschrift
Cardiovascular Research
Quellenangaben
Band: 89,
Heft: 4,
Seiten: 701-709
Verlag
Oxford University Press
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Human Genetics (IHG)