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Structural analysis of protein interfaces from ¹³C direct-detected paramagnetic relaxation enhancements.
J. Am. Chem. Soc. 132, 7285-7287 (2010)
The measurement of (13)C directed-detected paramagnetic relaxation enhancements (PREs) on spin-labeled proteins combines the efficacy of PREs for the detection of long-range distance information with the favorable sensitivity and resolution of (13)C direct-detected experiments. The (13)C PREs provide long-range distance restraints to map binding interfaces in proteins and protein complexes and are especially useful for studies of high-molecular weight perdeuterated molecules.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
ISSN (print) / ISBN
0002-7863
e-ISSN
1520-5126
Zeitschrift
Journal of the American Chemical Society
Quellenangaben
Band: 132,
Heft: 21,
Seiten: 7285-7287
Verlag
American Chemical Society (ACS)
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Structural Biology (STB)