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Anguita-Ruiz, A.* ; Plaza-Díaz, J.* ; Ruiz Ojeda, F.J. ; Rupérez, A.I.* ; Leis, R.* ; Bueno, G.* ; Gil-Campos, M.* ; Vázquez-Cobela, R.* ; Cañete, R.* ; Moreno, L.A.* ; Gil, A.* ; Aguilera, C.M.*

X chromosome genetic data in a Spanish children cohort, dataset description and analysis pipeline.

Sci. Data 6:130 (2019)
Verlagsversion Forschungsdaten DOI PMC
Open Access Gold
Creative Commons Lizenzvertrag
X chromosome genetic variation has been proposed as a potential source of missing heritability for many complex diseases, including obesity. Currently, there is a lack of public available genetic datasets incorporating X chromosome genotype data. Although several X chromosome-specific statistics have been developed, there is also a lack of readily available implementations for routine analysis. Here, we aimed: (1) to make public and describe a dataset incorporating phenotype and X chromosome genotype data from a cohort of 915 normal-weight, overweight and obese children, and (2) to deeply describe a whole implementation of the special X chromosome analytic process in genetics. Datasets and pipelines like this are crucial to get familiar with the steps in which X chromosome requires special attention and may raise awareness of the importance of this genomic region.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter Genome-wide Association; Dna Methylation; Inactivation; Expression; Obesity; Tests; Overweight; Landscape; Markers; Weight
ISSN (print) / ISBN 2052-4463
e-ISSN 2052-4463
Zeitschrift Scientific Data
Quellenangaben Band: 6, Heft: 1, Seiten: , Artikelnummer: 130 Supplement: ,
Verlag Nature Publishing Group
Verlagsort London
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Diabetes and Obesity (IDO)