Startseite
English
Erweiterte Suche
Durchblättern nach ...
Publikationen im Überblick
Ansprechpartner
Hilfe
DOI
 |
|
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Probing development and molecular function in diffusive living organisms with multispectral optoacoustic tomography (MSOT).
IFMBE Proc. 25/II, 921-924 (2009)
Optical interrogation of biological tissues offers great variety of intrinsic probing mechanisms as well as highly specific contrast approaches based on tissue-specific expression of fluorescent proteins and extrinsically administered moleculal biomarkers. Yet, most of the important living organisms and tissues remain inaccessible by the current optical imaging techniques due to complications arising from intense light scattering in tissues. In this work, a selective-plane illumination multispectral optoacoustic tomography (MSOT) technique was developed and applied for high-resolution whole-body visualization of intact mesoscopic-scale optically diffusive organisms whose sizes may vary from sub-millimeter up to a centimeter range and beyond. Utility of the method is demonstrated on several intact living organisms and small animal extremities. Furthermore, by combining multiwavelength illumination, the method is shown capable of resolving tissue-specific expression of fluorescent proteins located deep in optically diffuse tissues.
Altmetric
Weitere Metriken?
Zusatzinfos bearbeiten
[➜Einloggen]
Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Herausgeber
Dössel, O.* ; Schlegel, W.C.*
Schlagwörter
Small animal imaging; Optoacoustics; Photoacoustic tomography; Molecular imaging
ISSN (print) / ISBN
1680-0737
Zeitschrift
IFMBE Proceedings
Quellenangaben
Band: 25/II,
Seiten: 921-924
Reihe
IFMBE Proceedings
Verlag
Springer
Verlagsort
Berlin
Nichtpatentliteratur
Publikationen