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Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Ferroptose: Tod durch Eisenabhängige Lipidperoxidation.
BioSpektrum 25, 614-616 (2019)
Ferroptosis is an oxidative form of necrotic cell death highly relevant for many degenerative diseases and cancer. Ferroptosis is marked by iron-dependent lipid peroxidation and is distinct from other cell death modalities. Glutathione peroxidase 4 is the key ferroptosis player as it efficiently controls lipid peroxidation. Transgenic mice and animal models of disease have shown which cells and tissues are prone to undergo ferroptosis. The discovery of novel ferroptosis inhibitors and inducers thus offers the great potential in the development of innovative drugs to treat yet incurable diseases.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
ISSN (print) / ISBN
0947-0867
e-ISSN
1868-6249
Zeitschrift
BioSpektrum
Quellenangaben
Band: 25,
Heft: 6,
Seiten: 614-616
Verlag
Springer
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Developmental Genetics (IDG)