Non-invasive In-vivo sensing of metabolites with a novel Optoacoustic Spectroscope in the SWIR.
In: (European Conferences on Biomedical Optics, Munich, Germany). SPIE, 2019. (Proc. SPIE ; 11077)
In this work we developed a novel near-infrared two-path optoacoustic spectrometer (NiR-TAOS) that could sense OA intensity changes due to metabolite concentration changes in-vivo. The main aim of dividing the optical path in two is 1) perform real time correction of the laser emission profile of the laser source at different wavelengths and, 2) perform pulse to pulse correction to remove laser beam fluctuation and instability to increase signal to noise ratio. Signal to noise ratio improvement was significant not only at spectral peaks, but also at all other wavelengths. The system can be used for broad applications in biomedical measurements such as various metabolites in the SWIR.
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Publikationstyp
Artikel: Konferenzbeitrag
Dokumenttyp
Typ der Hochschulschrift
Herausgeber
Schlagwörter
Near-infrared Two-path Oas ; Non-invasive In-vivo Sensing Of Metabolites ; Optoacoustic ; Sensitivity And Specificity Improvement
Keywords plus
Sprache
englisch
Veröffentlichungsjahr
2019
Prepublished im Jahr
HGF-Berichtsjahr
2019
ISSN (print) / ISBN
0277-786X
e-ISSN
1996-756X
ISBN
Bandtitel
Konferenztitel
European Conferences on Biomedical Optics
Konferzenzdatum
Konferenzort
Munich, Germany
Konferenzband
Quellenangaben
Band: 11077
Heft: ,
Seiten: ,
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Supplement: ,
Reihe
Verlag
SPIE
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Prüfer
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Hochschule
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Veröffentlichungsdatum
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0000-00-00
Anmelder/Inhaber
weitere Inhaber
Anmeldeland
Priorität
Begutachtungsstatus
Peer reviewed
POF Topic(s)
30205 - Bioengineering and Digital Health
Forschungsfeld(er)
Enabling and Novel Technologies
PSP-Element(e)
G-505500-001
Förderungen
Copyright
Erfassungsdatum
2019-11-11