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Dean-Ben, X.L. ; Özbek, A. ; López-Schier, H.* ; Razansky, D.

Acoustic scattering mediated single detector optoacoustic tomography.

Phys. Rev. Lett. 123:174301 (2019)
Postprint DOI PMC
Open Access Green
Optoacoustic image formation is conventionally based upon ultrasound time-of-flight readings from multiple detection positions. Herein, we exploit acoustic scattering to physically encode the position of optical absorbers in the acquired signals, thus reducing the amount of data required to reconstruct an image from a single waveform. This concept is experimentally tested by including a random distribution of scatterers between the sample and an ultrasound detector array. Ultrasound transmission through a randomized scattering medium was calibrated by raster scanning a light-absorbing microparticle across a Cartesian grid. Image reconstruction from a single time-resolved signal was then enabled with a regularized model-based iterative algorithm relying on the calibration signals. The signal compression efficiency is facilitated by the relatively short acquisition time window needed to capture the entire scattered wave field. The demonstrated feasibility to form an image using a single recorded optoacoustic waveform paves a way to the development of faster and affordable optoacoustic imaging systems.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Photoacoustic Tomography; Time; Reconstruction; Algorithm
Sprache
Veröffentlichungsjahr 2019
HGF-Berichtsjahr 2019
ISSN (print) / ISBN 0031-9007
e-ISSN 1079-7114
Quellenangaben Band: 123, Heft: 17, Seiten: , Artikelnummer: 174301 Supplement: ,
Verlag American Physical Society (APS)
Verlagsort One Physics Ellipse, College Pk, Md 20740-3844 Usa
Begutachtungsstatus Peer reviewed
POF Topic(s) 30205 - Bioengineering and Digital Health
30204 - Cell Programming and Repair
Forschungsfeld(er) Enabling and Novel Technologies
Stem Cell and Neuroscience
PSP-Element(e) G-505590-001
G-500100-001
Scopus ID 85074453990
PubMed ID 31702258
Erfassungsdatum 2019-11-11