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Rühm, W. ; Breckow, J.* ; Dietze, G.* ; Friedl, A.* ; Greinert, R.* ; Jacob, P. ; Kistinger, S.* ; Michel, R.* ; Mueller, W.* ; Otten, H.* ; Streffer, C.* ; Weiss, W.*

Dose limits for occupational exposure to ionising radiation and genotoxic carcinogens: A German perspective.

Radiat. Environ. Biophys. 59, 9-27 (2020)
Postprint DOI PMC
Open Access Green
The paper includes a discussion of the reasoning behind current dose limits followed by a discussion of the detriment used by ICRP as a measure for stochastic health effects. Studies on radiation-induced cancer are reviewed because this endpoint represents the most important contribution to detriment. Recent findings on radiation-induced circulatory disease that are currently not included in detriment calculation are also reviewed. It appeared that for detriment calculations the contribution of circulatory diseases plays only a secondary role, although the uncertainties involved in their risk estimates are considerable. These discussions are complemented by a review of the procedures currently in use in Germany, or in discussion elsewhere, to define limits for genotoxic carcinogens. To put these concepts in perspective, actual occupational radiation exposures are exemplified with data from Germany, for the year 2012, and regulations in Germany are compared to the recommendations issued by ICRP. Conclusions include, among others, considerations on radiation protection concepts currently in use and recommendations of the SSK on the limitation of annual effective dose and effective dose cumulated over a whole working life.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Schlagwörter Dose Limits ; Genotoxic Carcinogens ; Ionising Radiation ; Radiation Protection; Solid Cancer Incidence; Atomic-bomb Survivors; Natural Background-radiation; Cardiovascular-diseases; Childhood Leukemia; Noncancer Mortality; Great-britain; Life-span; Mayak Pa; Cohort
Sprache englisch
Veröffentlichungsjahr 2020
Prepublished im Jahr 2019
HGF-Berichtsjahr 2019
ISSN (print) / ISBN 0301-634X
e-ISSN 1432-2099
Quellenangaben Band: 59, Heft: 1, Seiten: 9-27 Artikelnummer: , Supplement: ,
Verlag Springer
Verlagsort 233 Spring St, New York, Ny 10013 Usa
Begutachtungsstatus Peer reviewed
POF Topic(s) 30203 - Molecular Targets and Therapies
Forschungsfeld(er) Radiation Sciences
PSP-Element(e) G-501391-001
Scopus ID 85074725555
PubMed ID 31677018
Erfassungsdatum 2019-11-25