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Flexeder, C. ; Kabary Hassan, L. ; Standl, M. ; Schulz, H. ; Kühnisch, J.*

Is there an association between asthma and dental caries and molar incisor hypomineralisation?

Caries Res. 54, 87-95 (2020)
Verlagsversion Postprint DOI PMC
Open Access Green
This epidemiological study aimed to compare the caries and molar incisor hypomineralisation (MIH) experience in asthmatic and non-asthmatic adolescents assessed at 10 and 15 years of age. 730 adolescents from ongoing birth cohort studies (GINIplus/LISA) from Munich, Germany, were examined for carious lesions at the age of 10 and 15 years to determine caries experience under inclusion of non-cavitated carious lesions D1-2T and the tooth-related decay-missing-filled index. Furthermore, MIH was scored on all permanent teeth according to the criteria of the European Academy of Paediatric Dentistry. The association between caries and MIH prevalence at the 10-year and 15-year follow-up as well as caries incidence with ever having an asthma diagnosis was analysed using hurdle regression models adjusted for potential confounders. Of the 730 adolescents, 52 and 78 were identified as asthmatics at the 10- and 15-year follow-up, respectively. There were no significant differences in caries prevalence or experience between asthma-free participants and any of the asthma groups (taking metered-dose inhaler (MDI) medication vs. taking no MDI medication). However, a significant positive association was found for asthmatic adolescents who did not take MDI medication with higher MIH/T values (OR = 2.56, 95% CI = 1.03-6.37, p = 0.043) compared to non-asthmatics. In conclusion, asthma did not influence the caries status of adolescents in the present study. Interestingly, a significant association was found between adolescents with asthma who did not take MDI medication and the number of MIH-affected teeth. The association between asthma, medication, and MIH needs further confirmation.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter Caries ; Asthma ; Asthma Medication ; Inhalers ; Prevalence ; Cohort Study ; Epidemiology; Scoring System Univiss; Risk-factor; Children; Adolescents; Experience; Prevalence; Medication; Plaque; Mih
ISSN (print) / ISBN 0008-6568
e-ISSN 1421-976X
Zeitschrift Caries research
Quellenangaben Band: 54, Heft: 1, Seiten: 87-95 Artikelnummer: , Supplement: ,
Verlag Karger
Verlagsort Basel ; Freiburg [Breisgau] ; Paris ; London ; New York ; New Delhi ; Bangkok ; Singapore ; Tokyo ; Sydney
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Epidemiology (EPI)