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    Biophysical simulation tool partrac: Modelling proton beams at therapy-relevant energies.
        
        Radiat. Prot. Dosim. 186, 172-175 (2019)
    
    
    
				The biophysical simulation tool PARTRAC has been primarily developed to model radiation physics, chemistry and biology on nanometre to micrometre scales. However, the tool can be applied in simulating radiation effects in an event-by-event manner over macroscopic volumes as well. Benchmark simulations are reported showing that PARTRAC does reproduce the macroscopic Bragg peaks of proton beams, although the penetration depths are underestimated by a few per cent for high-energy beams. PARTRAC also quantifies the increase in DNA damage and its complexity along the beam penetration depth. Enhanced biological effectiveness is predicted in particular within distal Bragg peak parts of therapeutic proton beams.
			
			
		Impact Factor
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        Publikationstyp
        Artikel: Journalartikel
    
 
    
        Dokumenttyp
        Wissenschaftlicher Artikel
    
 
     
    
    
        Schlagwörter
        Photon; Repair
    
 
     
    
    
        Sprache
        englisch
    
 
    
        Veröffentlichungsjahr
        2019
    
 
     
    
        HGF-Berichtsjahr
        2019
    
 
    
    
        ISSN (print) / ISBN
        0144-8420
    
 
    
        e-ISSN
        1742-3406
    
 
     
     
     
	     
	 
	 
    
        Zeitschrift
        Radiation Protection Dosimetry
    
 
		
    
        Quellenangaben
        
	    Band: 186,  
	    Heft: 2-3,  
	    Seiten: 172-175 
	    
	    
	
    
 
  
         
        
            Verlag
            Oxford University Press
        
 
        
            Verlagsort
            Oxford
        
 
	
         
         
         
         
         
	
         
         
         
    
         
         
         
         
         
         
         
    
        Begutachtungsstatus
        Peer reviewed
    
 
    
        Institut(e)
        Institute of Radiation Medicine (IRM)
    
 
    
        POF Topic(s)
        30203 - Molecular Targets and Therapies
    
 
    
        Forschungsfeld(er)
        Radiation Sciences
    
 
    
        PSP-Element(e)
        G-501391-001
    
 
     
     	
    
    
        WOS ID
        WOS:000530582200006
    
    
        Scopus ID
        85082881470
    
    
        PubMed ID
        31808536
    
    
        Erfassungsdatum
        2019-12-09