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Jetzfellner, T. ; Razansky, D. ; Rosenthal, A.* ; Schulz, R.B.* ; Englmeier, K.-H. ; Ntziachristos, V.

Iterative finite-element-based inversion for quantified detection of molecular targets using optoacoustic tomography.

Proc. SPIE 7258, (Suppl.1)  :725812 (2009)
DOI
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
We describe an improved optoacoustic tomography method, that utilizes a diffusion-based photon propagation model in order to obtain quantified reconstruction of targets embedded deep in heterogeneous scattering and absorbing tissue. For the correction we utilize an iterative finite-element solution of the light diffusion equation to build a photon propagation model. We demonstrate image improvements achieved by this method by using tissue-mimicking phantom measurements. The particular strength of the method is its ability to achieve quantified reconstructions in non-uniform illumination configurations resembling whole-body small animal imaging scenarios.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Herausgeber Ehsan, S.* ; Jiang, H.*
Schlagwörter Finite Element Methods ; Iterative Methods ; Normalization Methods ; Optoacoustics ; Tomographic Imaging
ISSN (print) / ISBN 0277-786X
e-ISSN 1996-756X
Zeitschrift Proceedings of SPIE
Quellenangaben Band: 7258, Heft: , Seiten: , Artikelnummer: 725812, Supplement: (Suppl.1)  
Reihe Proceedings of SPIE
Verlag SPIE
Verlagsort Bellingham, WA
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Biological and Medical Imaging (IBMI)