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Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Continuous acquisition scanner for whole-body multispectral optoacoustic tomography.
Proc. SPIE 7564:756429 (2010)
Verlagsversion
DOI
An essential problem dealing with three-dimensional optoacoustic imaging is the long data acquisition times associated with recording signals from multiple spatial projections, where signal averaging for each projection is applied to obtain satisfying signal-to-noise-ratio. This approach complicates acquisition and makes imaging challenging for most applications, especially for in vivo imaging and multispectral imaging. Instead we employ a herein introduced continuous data acquisition methodology that greatly shortens recording times over multiple projection angles and acquires high quality tomographic data without averaging. By this means a two dimensional image acquisition having 270 angular projections only takes about 9 seconds, while a full multispectral three dimensional image can normally take about 15 minutes to acquire with a single ultrasonic detector. The system performance is verified on tissue-mimicking phantoms containing known concentrations of fluorescent molecular agent as well as small animals.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Herausgeber
Oraevsky, A. A.* ; Wang, L.V.*
Schlagwörter
Photoacoustic imaging; Biomedical Optics; Multispectral and hyperspectral imaging; Medical and biological imaging; Medical optics instrumentation
ISSN (print) / ISBN
0277-786X
e-ISSN
1996-756X
Zeitschrift
Proceedings of SPIE
Quellenangaben
Band: 7564,
Artikelnummer: 756429
Verlag
SPIE
Verlagsort
Bellingham, WA
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed