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Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
The proteasome system in health and disease.
Adv. Exp. Med. Biol. 1233, 55-100 (2020)
The proteasome is involved in the regulation of all cellular pathways and consequently plays a central role in the control of cellular homeostasis. Together with its regulators, it is at the frontline, both as an actor and as a target, in human health and when homeostasis is disturbed in disease. In this review, we aim to provide an overview of the many levels at which the functions of the proteasome and its regulators can be regulated to cope with cellular needs or are altered in pathological conditions.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Review
Schlagwörter
19s Complex ; Disease ; Pa200 ; Pa28 ; Pi31 ; Proteasome; Activator Reg-gamma; Multicatalytic Proteinase Complex; Endoplasmic-reticulum Stress; 26 S-proteasome; 20s Proteasome; Oxidative-stress; Cell-cycle; Nuclear Proteasome; Interferon-gamma; Cigarette-smoke
ISSN (print) / ISBN
0065-2598
Bandtitel
Proteostasis and Disease
Zeitschrift
Advances in Experimental Medicine and Biology
Quellenangaben
Band: 1233,
Seiten: 55-100
Verlag
Springer
Verlagsort
New York
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed
Institut(e)
Lung Health and Immunity (LHI)