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Spielmann, V. ; Li, W.B. ; Zankl, M. ; Ramos, J.C.O.* ; Petoussi-Henß, N.

Uncertainty analysis in internal dose calculations for cerium considering the uncertainties of biokinetic parameters and Svalues.

Radiat. Environ. Biophys. 59, 663–682 (2020)
Verlagsversion DOI PMC
Open Access Gold (Paid Option)
Creative Commons Lizenzvertrag
Radioactive cerium and other lanthanides can be transported through the aquatic system into foodstuffs and then be incorporated by humans. Information on the uncertainty of reported dose coefficients for exposed members of the public is then needed for risk analysis. In this study, uncertainties of dose coefficients due to the ingestion of the radionuclides(141)Ce and(144)Ce were estimated. According to the schema of internal dose calculation, a general statistical method based on the propagation of uncertainty was developed. The method takes into account the uncertainties contributed by the biokinetic models and by the so-calledSvalues. These S-values were derived by using Monte Carlo radiation transport simulations with five adult non-reference voxel computational phantoms that have been developed at Helmholtz Zentrum Munchen, Germany. Random and Latin hypercube sampling techniques were applied to sample parameters of biokinetic models and S values. The uncertainty factors, expressed as the square root of the 97.5th and 2.5th percentile ratios, for organ equivalent dose coefficients of(141)Ce were found to be in the range of 1.2-5.1 and for(144)Ce in the range of 1.2-7.4. The uncertainty factor of the detriment-weighted dose coefficient for(141)Ce is 2.5 and for(144)Ce 3.9. It is concluded that a general statistical method for calculating the uncertainty of dose coefficients was developed and applied to the lanthanide cerium. The dose uncertainties obtained provide improved dose coefficients for radiation risk analysis of humans. Furthermore, these uncertainties can be used to identify those parameters most important in internal dose calculations by applying sensitivity analyses.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter Uncertainty Quantification ; Internal Dosimetry ; Biokinetic Model ; Reference And Non-reference Phantoms; Absorbed Fractions; Reliability; Coefficients; Members; Model; Radionuclides; Exposure; Photon; Sr-90
ISSN (print) / ISBN 0301-634X
e-ISSN 1432-2099
Zeitschrift Radiation and Environmental Biophysics
Quellenangaben Band: 59, Heft: , Seiten: 663–682 Artikelnummer: , Supplement: ,
Verlag Springer
Verlagsort One New York Plaza, Suite 4600, New York, Ny, United States
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Radiation Medicine (IRM)
Förderungen Projekt DEAL