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Cutaneous barriers and skin immunity.
In:. Berlin ; Heidelberg: Springer, 2021. 43-52 (Handb. Exp. Pharmacol. ; 268)
The skin barrier provides us with several lines of protection from outside hazards. Its most outward layers, the stratum corneum and the epidermis seal our body with an acidic, dry, and rather cool surface, hostile to microbes. Yet, there are also fine-tuned interactions between the mostly commensal microbiota on top of the skin surface, with underlying epidermal cells as well as the immune system, to preserve a healthy steady state and to initiate repair processes when necessary. We take a concise look at the recent insights on the inner workings of this complex barrier.
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Anmerkungen
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Publikationstyp
Artikel: Sammelbandbeitrag/Buchkapitel
Schlagwörter
Immunity ; Microbiome ; Skin Barrier ; Staphylococcus
Sprache
englisch
Veröffentlichungsjahr
2021
HGF-Berichtsjahr
2021
ISSN (print) / ISBN
0171-2004
Zeitschrift
Handbook of Experimental Pharmacology
Quellenangaben
Band: 268,
Seiten: 43-52
Verlag
Springer
Verlagsort
Berlin ; Heidelberg
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute for Allergy Research (IAF)
POF Topic(s)
30202 - Environmental Health
Forschungsfeld(er)
Allergy
PSP-Element(e)
G-522200-001
Scopus ID
85119658279
PubMed ID
34114118
Erfassungsdatum
2021-07-19