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Hu, T.T.* ; Pattyn, P.* ; Bakker, E.G.* ; Cao, J.* ; Cheng, J.F.* ; Clark, R.M.* ; Fahlgren, N.* ; Fawcett, J.A.* ; Grimwood, J.* ; Gundlach, H. ; Haberer, G. ; Hollister, JD.* ; Ossowski, S.* ; Ottilar, R.P.* ; Salamov, A.A.* ; Schneeberger, K.* ; Spannagl, M. ; Wang, X. ; Yang, L.* ; Nasrallah, M.E.* ; Bergelson, J.* ; Carrington, J.C.* ; Gaut, B.S.* ; Schmutz, J.* ; Mayer, K.F.X. ; van de Peer, Y.* ; Grigoriev, I.V.* ; Nordborg, M.* ; Weigel, D.* ; Guo, Y.L.*

The Arabidopsis lyrata genome sequence and the basis of rapid genome size change.

Nat. Genet. 43, 476-481 (2011)
DOI PMC
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
We report the 207-Mb genome sequence of the North American Arabidopsis lyrata strain MN47 based on 8.3x dideoxy sequence coverage. We predict 32,670 genes in this outcrossing species compared to the 27,025 genes in the selfing species Arabidopsis thaliana. The much smaller 125-Mb genome of A. thaliana, which diverged from A. lyrata 10 million years ago, likely constitutes the derived state for the family. We found evidence for DNA loss from large-scale rearrangements, but most of the difference in genome size can be attributed to hundreds of thousands of small deletions, mostly in noncoding DNA and transposons. Analysis of deletions and insertions still segregating in A. thaliana indicates that the process of DNA loss is ongoing, suggesting pervasive selection for a smaller genome. The high-quality reference genome sequence for A. lyrata will be an important resource for functional, evolutionary and ecological studies in the genus Arabidopsis.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter transposal elements; DNA loss; angiosperm genomes; eucariotic genome; thaliana; evolution; plants; aligmentT; identification; expansion
ISSN (print) / ISBN 1061-4036
e-ISSN 1546-1718
Zeitschrift Nature Genetics
Quellenangaben Band: 43, Heft: 5, Seiten: 476-481 Artikelnummer: , Supplement: ,
Verlag Nature Publishing Group
Verlagsort New York, NY
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed