PuSH - Publikationsserver des Helmholtz Zentrums München

Export: TXT Text RIS Endnote (RIS) BIB BibTeX
Mootz, M. ; Jakwerth, C.A. ; Schmidt-Weber, C.B. ; Zissler, U.M.

Secretoglobins in the big picture of immunoregulation in airway diseases.

Allergy 77, 767-777 (2022)
Verlagsversion DOI PMC
Open Access Hybrid
Creative Commons Lizenzvertrag
The proteins of the secretoglobin (SCGB) family are expressed by secretory tissues of barrier organs. They are embedded in immunoregulatory and anti-inflammatory processes of airway diseases. This review particularly illustrates the immune regulation of SCGBs by cytokines and their implication in the pathophysiology of airway diseases. The biology of SCGBs is a complex topic of increasing importance, as they are highly abundant in the respiratory tract and can also be detected in malignant tissues and as elements of immune control. In addition, SCGBs react to cytokines, they are embedded in Th1 and Th2 immune responses, and they are expressed in a manner dependent on cell maturation. The big picture of the SCGB family identifies these factors as critical elements of innate immune control at the epithelial barriers and highlights their potential for diagnostic assessment of epithelial activity. Some members of the SCGB family have so far only been superficially examined, but have high potential for translational research.
Impact Factor
Scopus SNIP
Altmetric
14.710
0.000
Tags
Anmerkungen
Besondere Publikation
Auf Hompepage verbergern

Zusatzinfos bearbeiten
Eigene Tags bearbeiten
Privat
Eigene Anmerkung bearbeiten
Privat
Auf Publikationslisten für
Homepage nicht anzeigen
Als besondere Publikation
markieren
Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Schlagwörter Scgb1a1 ; Secretoglobin ; Th1 ; Th2 ; Allergic Rhinitis ; Allergy ; Asthma; Cell Secretory Protein; Uteroglobin-related Protein-1; 10 Kda Protein; Clara Cell; Mammaglobin-b; Gene-expression; Bronchoalveolar Lavage; Inflammatory Response; Lung Inflammation; Epithelial Injury
Sprache englisch
Veröffentlichungsjahr 2022
Prepublished im Jahr 2021
HGF-Berichtsjahr 2021
ISSN (print) / ISBN 0105-4538
e-ISSN 1398-9995
Zeitschrift Allergy
Quellenangaben Band: 77, Heft: 3, Seiten: 767-777 Artikelnummer: , Supplement: ,
Verlag Wiley
Verlagsort 111 River St, Hoboken 07030-5774, Nj Usa
Begutachtungsstatus Peer reviewed
Institut(e) Institute for Allergy Research (IAF)
POF Topic(s) 30202 - Environmental Health
Forschungsfeld(er) Allergy
PSP-Element(e) G-505400-001
Förderungen German Research Foundation (DFG)
German Center for Lung Research (DZL)
DOI 10.1111/all.15033
WOS ID WOS:000683767300001
Scopus ID 85112118262
PubMed ID 34343347
Erfassungsdatum 2021-09-16
[➜Korrektur melden]