PuSH - Publikationsserver des Helmholtz Zentrums München

Export: TXT Text RIS Endnote (RIS) BIB BibTeX
Jiang, D. ; Rinkevich, Y.

Furnishing wound repair by the subcutaneous fascia.

Int. J. Mol. Sci. 22:9006 (2021)
Verlagsversion DOI PMC
Open Access Gold
Creative Commons Lizenzvertrag
Mammals rapidly heal wounds through fibrous connective tissue build up and tissue contraction. Recent findings from mouse attribute wound healing to physical mobilization of a fibroelastic connective tissue layer that resides beneath the skin, termed subcutaneous fascia or superficial fascia, into sites of injury. Fascial mobilization assembles diverse cell types and matrix components needed for rapid wound repair. These observations suggest that the factors directly affecting fascial mobility are responsible for chronic skin wounds and excessive skin scarring. In this review, we discuss the link between the fascia's unique tissue anatomy, composition, biomechanical, and rheologic properties to its ability to mobilize its tissue assemblage. Fascia is thus at the forefront of tissue pathology and a better understanding of how it is mobilized may crystallize our view of wound healing alterations during aging, diabetes, and fibrous disease and create novel therapeutic strategies for wound repair.
Impact Factor
Scopus SNIP
Scopus
Cited By
Altmetric
5.923
1.441
1
Tags
Anmerkungen
Besondere Publikation
Auf Hompepage verbergern

Zusatzinfos bearbeiten
Eigene Tags bearbeiten
Privat
Eigene Anmerkung bearbeiten
Privat
Auf Publikationslisten für
Homepage nicht anzeigen
Als besondere Publikation
markieren
Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Schlagwörter Fascia ; Fibrosis ; Scar ; Skin ; Subcutaneous Fascia ; Superficial Fascia ; Wound Healing; Neuropathic Diabetic-patients; Granulation-tissue; Connective-tissue; Hypertrophic Scar; Skin; Regeneration; Hyaluronan; Mechanotransduction; Acupuncture; Fibroblasts
Sprache englisch
Veröffentlichungsjahr 2021
HGF-Berichtsjahr 2021
ISSN (print) / ISBN 1661-6596
e-ISSN 1422-0067
Zeitschrift International Journal of Molecular Sciences
Quellenangaben Band: 22, Heft: 16, Seiten: , Artikelnummer: 9006 Supplement: ,
Verlag MDPI
Verlagsort Basel
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Lung Health and Immunity (LHI)
POF Topic(s) 30202 - Environmental Health
Forschungsfeld(er) Lung Research
PSP-Element(e) G-554000-001
Förderungen European Research Council
Deutsche Forschungsgemeinschaft
Human Frontier Science Program
DOI 10.3390/ijms22169006
WOS ID WOS:000689061400001
Scopus ID 85113639133
PubMed ID 34445709
Erfassungsdatum 2021-09-27
[➜Korrektur melden]