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Evolutionary conservation and cell type specificity of nuclear compartments in the brain.
Trends Neurosci. 45, 3-5 (2021)
In the cell nucleus, radial genome organization relative to the nuclear lamina exhibits both cell type–specific variability and evolutionarily conserved distribution. A recent study by Ahanger, Delgado et al. explores the in vivo spatial distribution of the genome in the brain and identifies conserved genomic localization across mammalian species that are correlated with gene expression states.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Letter to the Editor
Schlagwörter
Human Cortex ; Lamin B ; Lamina-associated Domain (lad) ; Spatial Genome Organization ; Speckle-associated Domain (spad); Organization; Dynamics
ISSN (print) / ISBN
0166-2236
e-ISSN
1878-108X
Zeitschrift
Trends in Neurosciences
Quellenangaben
Band: 45,
Heft: 1,
Seiten: 3-5
Verlag
Elsevier
Verlagsort
Amsterdam [u.a.]
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed
Institut(e)
Helmholtz Pioneer Campus (HPC)
Förderungen
Helmholtz Pioneer Campus
HelmholtzGemeinschaft
DFG
HelmholtzGemeinschaft
DFG