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Track structures, DNA targets and radiation effects in the biophysical Monte Carlo simulation code PARTRAC.
Mutat. Res. -Fund. Mol. Mech. Mutag. 711, 28-40 (2011)
This review describes the PARTRAC suite of comprehensive Monte Carlo simulation tools for calculations of track structures of a variety of ionizing radiation qualities and their biological effects. A multi-scale target model characterizes essential structures of the whole genomic DNA within human fibroblasts and lymphocytes in atomic resolution. Calculation methods and essential results are recapitulated regarding the physical, physico-chemical and chemical stage of track structure development of radiation damage induction. Recent model extension towards DNA repair processes extends the time dimension by about 12 orders of magnitude and paves the way for superior predictions of radiation risks.
Impact Factor
Scopus SNIP
Web of Science
Times Cited
Times Cited
Scopus
Cited By
Cited By
Altmetric
3.204
1.128
102
254
Anmerkungen
Besondere Publikation
Auf Hompepage verbergern
Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Schlagwörter
Modelling; Track structure; Multi-scale; DNA damage; DNA repair
Sprache
Veröffentlichungsjahr
2011
HGF-Berichtsjahr
2011
ISSN (print) / ISBN
0027-5107
e-ISSN
1873-135X
Quellenangaben
Band: 711,
Heft: 1-2,
Seiten: 28-40
Verlag
Elsevier
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Radiation Protection (ISS)
POF Topic(s)
30504 - Mechanisms of Genetic and Environmental Influences on Health and Disease
Forschungsfeld(er)
Radiation Sciences
PSP-Element(e)
G-501100-004
PubMed ID
21281649
Scopus ID
79956189193
Erfassungsdatum
2011-07-26