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Starke, S.* ; Thalmeier, D. ; Steinbach, P.* ; Piraud, M.

A hybrid radiomics approach to modeling progression-free survival in head and neck cancers.

In: (HECKTOR 2021: Head and Neck Tumor Segmentation and Outcome Prediction, Virtual, Online). Berlin [u.a.]: Springer, 2022. 266-277 (Lect. Notes Comput. Sc. ; 13209 LNCS)
DOI
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
We present our contribution to the HECKTOR 2021 challenge. We created a Survival Random Forest model based on clinical features, and a few radiomics features that have been extracted with and without using the given tumor masks, for Task 3 and Task 2 of the challenge, respectively. To decide on which radiomics features to include into the model, we proceeded both to automatic feature selection, using several established methods, and to literature review of radiomics approaches for similar tasks. Our best performing model includes one feature selected from the literature (Metabolic Tumor Volume derived from the FDG-PET image), one via stability selection (Inverse Variance of the Gray Level Co-occurrence Matrix of the CT image), and one selected via permutation-based feature importance (Tumor Sphericity). This hybrid approach turns-out to be more robust to overfitting than models based on automatic feature selection. We also show that simple ROI definition for the radiomics features, derived by thresholding the Standard Uptake Value in the FDG-PET images, outperforms the given expert tumor delineation in our case.
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Publikationstyp Artikel: Konferenzbeitrag
Korrespondenzautor
Schlagwörter Progression-free Survival ; Radiomics ; Survival Random Forests
ISSN (print) / ISBN 0302-9743
e-ISSN 1611-3349
Konferenztitel HECKTOR 2021: Head and Neck Tumor Segmentation and Outcome Prediction
Konferenzort Virtual, Online
Zeitschrift Lecture Notes in Computer Science
Quellenangaben Band: 13209 LNCS, Heft: , Seiten: 266-277 Artikelnummer: , Supplement: ,
Verlag Springer
Verlagsort Berlin [u.a.]
Nichtpatentliteratur Publikationen
Institut(e) Helmholtz Artifical Intelligence Cooperation Unit (HAICU)