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Cahill, N.D.* ; Schnabel, J.A.* ; Noble, J.A.* ; Hawkes, D.J.*

Revisiting overlap invariance in medical image alignment.

In: (2008 IEEE Computer Society Conference on Computer Vision and Pattern Recognition Workshops, 23-28 June 2008, Anchorage, AK, USA). 2008. (2008 IEEE Computer Society Conference on Computer Vision and Pattern Recognition Workshops, CVPR Workshops)
DOI
In[8], Studholme et al. introduced normalized mutual information (NMI) as an overlap invariant generalization of mutual information (MI). Even though Studholme showed how NMI could be used effectively in multimodal medical image alignment, the overlap invariance was only established empirically on a few simple examples. In this paper, we illustrate a simple example in which NMI fails to be invariant to changes in overlap size, as do other standard similarity measures including MI, cross correlation (CCorr), correlation coefficient (CCoeff), correlation ratio (CR), and entropy correlation coefficient (ECC). We then derive modified forms of all of these similarity measures that are proven to be invariant to changes in overlap size. This is done by making certain assumptions about background statistics. Experiments on multimodal rigid registration of brain images1 show that 1) most of the modified similarity measures outperform their standard forms, and 2) the modified version of MI exhibits superior performance over any of the other similarity measures for both CT/MR and PET/MR registration. © 2008 IEEE.
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Publikationstyp Artikel: Konferenzbeitrag
Korrespondenzautor
Konferenztitel 2008 IEEE Computer Society Conference on Computer Vision and Pattern Recognition Workshops
Konferzenzdatum 23-28 June 2008
Konferenzort Anchorage, AK, USA
Nichtpatentliteratur Publikationen
Institut(e) Institute for Machine Learning in Biomed Imaging (IML)