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Comas-Armangue, G. ; Makharadze, L. ; Gómez Velázquez, M. ; Teperino, R.

The legacy of parental obesity: Mechanisms of non-genetic transmission and reversibility.

Biomedicines 10:2461 (2022)
Verlagsversion DOI PMC
Open Access Gold
Creative Commons Lizenzvertrag
While a dramatic increase in obesity and related comorbidities is being witnessed, the underlying mechanisms of their spread remain unresolved. Epigenetic and other non-genetic mechanisms tend to be prominent candidates involved in the establishment and transmission of obesity and associated metabolic disorders to offspring. Here, we review recent findings addressing those candidates, in the context of maternal and paternal influences, and discuss the effectiveness of preventive measures.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Korrespondenzautor
Schlagwörter Dohad ; Epigenetics ; Hfd ; Intergenerational Inheritance ; Non-genetic Inheritance ; Obesity ; Pohad ; Reversibility
ISSN (print) / ISBN 2227-9059
e-ISSN 2227-9059
Zeitschrift Biomedicines
Quellenangaben Band: 10, Heft: 10, Seiten: , Artikelnummer: 2461 Supplement: ,
Verlag MDPI
Verlagsort Basel, Switzerland
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Experimental Genetics (IEG)
Förderungen Helmholtz Association
Fritz Thyssen Stiftung
German Diabetes Research Center