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Liao, M. ; Mu, Y.* ; Su, X.* ; Zheng, L.* ; Zhang, S.* ; Chen, H.* ; Xu, S.* ; Ma, J.* ; OuYang, R.Q.* ; Li, W.* ; Cheng, C.* ; Cai, J.* ; Chen, Y.* ; Wang, C.* ; Zeng, F.

Association between branched-chain amino acid intake and physical function among Chinese community-dwelling elderly residents.

Nutrients 14:4367 (2022)
Verlagsversion Forschungsdaten DOI PMC
Open Access Gold
Creative Commons Lizenzvertrag
This study aimed to evaluate the potential associations of dietary BCAAs (isoleucine, leucine, and valine) with physical function in the elderly Chinese population. A validated semiquantitative food frequency questionnaire and anthropometric and physical function measurements were used to collect data. We modeled trends in physical function indicators for BCAA quartiles using multivariate linear regression models. Among 4336 (43.97% men) participants aged 72.73 ± 5.48 years, a higher dietary intake of BCAAs was positively associated with increased handgrip strength (all p trends < 0.001), shorter times for 4-m fast walking (all p trends < 0.001) and repeated chair rises (all p trends < 0.001). No linear association was found between subtypes of amino acids and any physical functions (all p trends > 0.05). Individuals in the highest quartiles of BCAA intake had a reduced risk of developing low muscle strength, and the multiadjusted odds ratios (ORs) and 95% confidence intervals (95% CIs) for women and men were 0.50 (0.38–0.65) and 0.67 (0.50–0.91), respectively. Similarly, higher BCAA consumption was associated with a lower risk of developing low physical performance (4-m walking speed: OR = 0.68 [0.50–0.93]; repeated chair rises: OR = 0.66 [0.54–0.81]). Higher dietary BCAA intake might be beneficial for physical function in the elderly population.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter Branched-chain Amino Acids ; Elderly Population ; Muscle Strength ; Physical Function
ISSN (print) / ISBN 2072-6643
e-ISSN 2072-6643
Zeitschrift Nutrients
Quellenangaben Band: 14, Heft: 20, Seiten: , Artikelnummer: 4367 Supplement: ,
Verlag MDPI
Verlagsort Basel
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Epidemiology II (EPI2)
Förderungen Shenzhen science and technology project
Nanshan Health Science and Technology Plan
Nanshan Regional Discipline Alliance Construction Project
the Nanshan Medical Key Discipline Construction Funding (Noninfectious Chronic Disease), Sanming Project of Medicine in Shenzhen