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Ye, H. ; Rinkevich, Y.

Fascia layer-a novel target for the application of biomaterials in skin wound healing.

Int. J. Mol. Sci. 24:15 (2023)
Verlagsversion DOI PMC
Open Access Gold
Creative Commons Lizenzvertrag
As the first barrier of the human body, the skin has been of great concern for its wound healing and regeneration. The healing of large, refractory wounds is difficult to be repaired by cell proliferation at the wound edges and usually requires manual intervention for treatment. Therefore, therapeutic tools such as stem cells, biomaterials, and cytokines have been applied to the treatment of skin wounds. Skin microenvironment modulation is a key technology to promote wound repair and skin regeneration. In recent years, a series of novel bioactive materials that modulate the microenvironment and cell behavior have been developed, showing the ability to efficiently facilitate wound repair and skin attachment regeneration. Meanwhile, our lab found that the fascial layer has an indispensable role in wound healing and repair, and this review summarizes the research progress of related bioactive materials and their role in wound healing.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Korrespondenzautor
Schlagwörter Biomaterials ; Fascia Layer ; New Target ; Wound Healing; Mesoporous Bioactive Glass; Mast-cells; Subcutaneous Tissue; Dermal Fibroblasts; Keratinocytes; Angiogenesis; Regeneration; Scaffolds; Matrix; Nanocomposites
ISSN (print) / ISBN 1422-0067
e-ISSN 1661-6596
Zeitschrift International Journal of Molecular Sciences
Quellenangaben Band: 24, Heft: 3, Seiten: , Artikelnummer: 15 Supplement: ,
Verlag MDPI
Verlagsort Basel
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Regenerative Biology and Medicine (IRBM)
Förderungen European Foundation
LEO Foundation
European Research Council