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Krefting, D.* ; Anton, G. ; Chaplinskaya-Sobol, I.* ; Hanss, S.* ; Hoffmann, W.* ; Hopff, S.M.* ; Kraus, M. ; Lorbeer, R.* ; Lorenz-Depiereux, B. ; Illig, T.* ; Schäfer, C.* ; Schaller, J.* ; Stahl, D.* ; Valentin, H.* ; Heuschmann, P.* ; Vehreschild, J.*

The importance of being FAIR and FAST – The clinical epidemiology and study platform of the German network university medicine (NUKLEUS).

Stud. Health Technol. Inform. 302, 93-97 (2023)

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The COVID-19 pandemic has urged the need to set up, conduct and analyze high-quality epidemiological studies within a very short time-scale to provide timely evidence on influential factors on the pandemic, e.g. COVID-19 severity and disease course. The comprehensive research infrastructure developed to run the German National Pandemic Cohort Network within the Network University Medicine is now maintained within a generic clinical epidemiology and study platform NUKLEUS. It is operated and subsequently extended to allow efficient joint planning, execution and evaluation of clinical and clinical-epidemiological studies. We aim to provide high-quality biomedical data and biospecimens and make its results widely available to the scientific community by implementing findability, accessibility, interoperability and reusability - i.e. following the FAIR guiding principles. Thus, NUKLEUS might serve as role model for FAIR and fast implementation of clinical epidemiological studies within the setting of University Medical Centers and beyond.

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