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Azzini, A.M.* ; Canziani, L.M.* ; Davis, R.J.* ; Mirandola, M.* ; Hoelscher, M.* ; Meyer, L.* ; Laouénan, C.* ; Giannella, M.* ; Rodríguez-Baño, J.* ; Boffetta, P.* ; Mates, D.* ; Malhotra-Kumar, S.* ; Scipione, G.* ; Stellmach, C.* ; Rinaldi, E.* ; Hasenauer, J. ; Tacconelli, E.*

How european research projects can support vaccination strategies: The case of the ORCHESTRA project for SARS-CoV-2.

Vaccines 11:8 (2023)
Verlagsversion DOI PMC
Open Access Gold
Creative Commons Lizenzvertrag
ORCHESTRA ("Connecting European Cohorts to Increase Common and Effective Response To SARS-CoV-2 Pandemic") is an EU-funded project which aims to help rapidly advance the knowledge related to the prevention of the SARS-CoV-2 infection and the management of COVID-19 and its long-term sequelae. Here, we describe the early results of this project, focusing on the strengths of multiple, international, historical and prospective cohort studies and highlighting those results which are of potential relevance for vaccination strategies, such as the necessity of a vaccine booster dose after a primary vaccination course in hematologic cancer patients and in solid organ transplant recipients to elicit a higher antibody titer, and the protective effect of vaccination on severe COVID-19 clinical manifestation and on the emergence of post-COVID-19 conditions. Valuable data regarding epidemiological variations, risk factors of SARS-CoV-2 infection and its sequelae, and vaccination efficacy in different subpopulations can support further defining public health vaccination policies.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Covid-19 ; Cohort Study ; Data Harmonization ; Fragile Population ; Healthcare Workers ; Public Health ; Vaccination
Sprache englisch
Veröffentlichungsjahr 2023
HGF-Berichtsjahr 2023
e-ISSN 2076-393X
Zeitschrift Vaccines
Quellenangaben Band: 11, Heft: 8 Seiten: , Artikelnummer: 8 Supplement: ,
Verlag MDPI
Verlagsort Basel
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Computational Biology (ICB)
POF Topic(s) 30205 - Bioengineering and Digital Health
Forschungsfeld(er) Enabling and Novel Technologies
PSP-Element(e) G-553800-001
Förderungen European Union
DOI 10.3390/vaccines11081361
WOS ID 001056876100001
Scopus ID 85169067100
PubMed ID 37631929
Erfassungsdatum 2023-10-06
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