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Xiong, Y.* ; Feng, Q.* ; Lu, L.* ; Qiu, X.* ; Knoedler, S. ; Panayi, A.C.* ; Jiang, D. ; Rinkevich, Y. ; Lin, Z.* ; Mi, B.* ; Liu, G.* ; Zhao, Y.*

Metal-organic frameworks and their composites for chronic wound healing: From bench to bedside.

Adv. Mater. 36:e2302587 (2023)
Verlagsversion DOI PMC
Chronic wounds are characterized by delayed and dysregulated healing processes. As such, they have emerged as an increasingly significant threat. The associated morbidity and socioeconomic toll are clinically and financially challenging, necessitating novel approaches in the management of chronic wounds. Metal-organic frameworks (MOFs) are an innovative type of porous coordination polymers, with low toxicity and high eco-friendliness. Documented anti-bacterial effects and pro-angiogenic activity predestine these nanomaterials as promising systems for the treatment of chronic wounds. In this context, the therapeutic applicability and efficacy of MOFs remain to be elucidated. We, therefore, review structural-functional properties of MOFs and their composite materials and discuss how their multifunctionality and customizability could be leveraged as a clinical therapy for chronic wounds. This article is protected by copyright. All rights reserved.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Schlagwörter Biomaterials ; Chronic Wounds ; Metal-organic Frameworks ; Multifunctionality ; Nanomedicine; Tissue-repair; Bacteria; Nanoparticles; Regeneration; Hydrogels; Release; Acid
Sprache englisch
Veröffentlichungsjahr 2023
HGF-Berichtsjahr 2023
ISSN (print) / ISBN 0935-9648
e-ISSN 1521-4095
Zeitschrift Advanced materials
Quellenangaben Band: 36, Heft: 2, Seiten: , Artikelnummer: e2302587 Supplement: ,
Verlag Wiley
Verlagsort Weinheim
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Regenerative Biology and Medicine (IRBM)
POF Topic(s) 30202 - Environmental Health
Forschungsfeld(er) Lung Research
PSP-Element(e) G-509400-001
Förderungen European Union
German Research Foundation
China Postdoctoral Science Foundation
Hubei Province Key Laboratory of Oral and Maxillofacial Development and Regeneration
National Science Foundation of China
Y.X. and Q.F. contributed equally to this work. This work was supported by the National Science Foundation of China (No. 82002313, 82072444, 31900963, and 82202714), the Hubei Province Key Laboratory of Oral and Maxillofacial Development and Regeneration
Scopus ID 85175992710
PubMed ID 37527058
Erfassungsdatum 2023-10-06