Hinweise zu Qualitätskriterien von Zeitschriften
Open-Access-Richtlinie der Helmholtz-Gemeinschaft 2016
CC Licencences
Metriken für Publikationen
Startseite
Login
English
Neuer EVA Antrag
Erweiterte Suche
Durchblättern nach ...
Publikationen im Überblick
HGF Fortschrittsbericht
OA Publikationen
Neue Publikation eintragen
Neue Publikation holen aus...
Fehlende Publikation melden
Ansprechpartner
Hilfe
Bibliometrische Indikatoren
Text
Endnote (RIS)
BibTeX
DOI
 |
|
möglich sobald bei der ZB eingereicht worden ist.
Aging and regeneration in the lung – Significance for COPD.
Atemwegs- Lungenkr. 49, 140-146 (2023)
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. Lung transplantation remains the only curative option for patients with end-stage disease. A missing understanding of pathomechanisms and phenotypes of COPD hampers the development of novel therapeutic approaches. COPD is a disease of the aging population and is characterized by impaired regenerative capacity of the lung. Regenerative capacity is reduced in the aging lung which is caused by different cellular processes. Among those, cellular senescence is a main mechanism which is increased in COPD lungs. Cellular senescence impairs stem cell capacity and contributes to aging-associated chronic inflammation, so-called inflammaging. The therapeutic targeting of cellular senescence showed first promising results in preclinical experiments and suggests cellular senescence as a main target for personalized medicine approaches aiming at restoring the regenerative capacity of the COPD lung.
Impact Factor
Scopus SNIP
Altmetric
0.000
0.035
Anmerkungen
Besondere Publikation
Auf Hompepage verbergern
Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Review
Schlagwörter
Aging ; Cellular Senescence ; Copd ; Regeneration ; Senolytics
Sprache
deutsch
Veröffentlichungsjahr
2023
HGF-Berichtsjahr
2023
ISSN (print) / ISBN
0341-3055
e-ISSN
0341-3055
Zeitschrift
Atemwegs- und Lungenkrankheiten
Quellenangaben
Band: 49,
Heft: 4,
Seiten: 140-146
Verlag
Dustri
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Lung Health and Immunity (LHI)
POF Topic(s)
30202 - Environmental Health
Forschungsfeld(er)
Lung Research
PSP-Element(e)
G-501600-005
Scopus ID
85161283516
Erfassungsdatum
2023-12-12