PuSH - Publikationsserver des Helmholtz Zentrums München

Export: TXT Text RIS Endnote (RIS) BIB BibTeX
Liu, C.* ; Chen, R.* ; Sera, F.* ; Vicedo-Cabrera, A.M.* ; Guo, Y.* ; Tong, S.* ; Lavigne, E.* ; Correa, P.M.* ; Ortega, N.V.* ; Achilleos, S.* ; Royé, D.* ; Jaakkola, J.J.* ; Ryti, N.* ; Pascal, M.* ; Schneider, A.E. ; Breitner-Busch, S. ; Entezari, A.* ; Mayvaneh, F.* ; Raz, R.* ; Honda, Y.* ; Hashizume, M.* ; Ng, C.F.S.* ; Gaio, V.* ; Madureira, J.* ; Holobaca, I.H.* ; Tobias, A.* ; Iñiguez, C.* ; Guo, Y.L.* ; Pan, S.C.* ; Masselot, P.* ; Bell, M.L.* ; Zanobetti, A.* ; Schwartz, J.* ; Gasparrini, A.* ; Kan, H.*

Interactive effects of ambient fine particulate matter and ozone on daily mortality in 372 cities: Two stage time series analysis.

BMJ 383:e075203 (2023)
Verlagsversion DOI PMC
Open Access Hybrid
Creative Commons Lizenzvertrag
OBJECTIVE: To investigate potential interactive effects of fine particulate matter (PM2.5) and ozone (O3) on daily mortality at global level. DESIGN: Two stage time series analysis. SETTING: 372 cities across 19 countries and regions. POPULATION: Daily counts of deaths from all causes, cardiovascular disease, and respiratory disease. MAIN OUTCOME MEASURE: Daily mortality data during 1994-2020. Stratified analyses by co-pollutant exposures and synergy index (>1 denotes the combined effect of pollutants is greater than individual effects) were applied to explore the interaction between PM2.5 and O3 in association with mortality. RESULTS: During the study period across the 372 cities, 19.3 million deaths were attributable to all causes, 5.3 million to cardiovascular disease, and 1.9 million to respiratory disease. The risk of total mortality for a 10 μg/m3 increment in PM2.5 (lag 0-1 days) ranged from 0.47% (95% confidence interval 0.26% to 0.67%) to 1.25% (1.02% to 1.48%) from the lowest to highest fourths of O3 concentration; and for a 10 μg/m3 increase in O3 ranged from 0.04% (-0.09% to 0.16%) to 0.29% (0.18% to 0.39%) from the lowest to highest fourths of PM2.5 concentration, with significant differences between strata (P for interaction <0.001). A significant synergistic interaction was also identified between PM2.5 and O3 for total mortality, with a synergy index of 1.93 (95% confidence interval 1.47 to 3.34). Subgroup analyses showed that interactions between PM2.5 and O3 on all three mortality endpoints were more prominent in high latitude regions and during cold seasons. CONCLUSION: The findings of this study suggest a synergistic effect of PM2.5 and O3 on total, cardiovascular, and respiratory mortality, indicating the benefit of coordinated control strategies for both pollutants.
Impact Factor
Scopus SNIP
Web of Science
Times Cited
Scopus
Cited By
Altmetric
107.700
0.000
4
3
Tags
Anmerkungen
Besondere Publikation
Auf Hompepage verbergern

Zusatzinfos bearbeiten
Eigene Tags bearbeiten
Privat
Eigene Anmerkung bearbeiten
Privat
Auf Publikationslisten für
Homepage nicht anzeigen
Als besondere Publikation
markieren
Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Air-pollution; Particles; Health
Sprache englisch
Veröffentlichungsjahr 2023
HGF-Berichtsjahr 2023
ISSN (print) / ISBN 0959-535X
e-ISSN 1756-1833
Zeitschrift BMJ
Quellenangaben Band: 383, Heft: , Seiten: , Artikelnummer: e075203 Supplement: ,
Verlag British Medical Association
Verlagsort London
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Epidemiology (EPI)
POF Topic(s) 30202 - Environmental Health
Forschungsfeld(er) Genetics and Epidemiology
PSP-Element(e) G-504000-001
Förderungen Italian Ministry of University and Research, Department of Excellence project 2023-2027 ReDS "Rethinking Data Science" - Department of Statistics, Computer Science and Applications - University of Florence
National Natural Science Foundation of China
DOI 10.1136/bmj-2023-075203
WOS ID 001102353800001
Scopus ID 85174324211
PubMed ID 37793695
Erfassungsdatum 2023-11-28
[➜Korrektur melden]